130607-86-2

Upstream product

• 2181-44-4 trimethylsulfonium methylsulfate 
• 130693-79-7 (+)-(3S,6S)-2,2,3,6-tetramethyl-1-cyclohexanone 

Downstream Products

• 153061-01-9 (-)-(1S,3S,6S)-2,2,3,6-tetramethylcyclohexane-1-carbaldehyde 
• 139406-65-8 (+)-(1R,3S,6S)-2,2,3,6-tetramethylcyclohexane-1-carbaldehyde 
• 153061-06-4 (+)-(1'S,3'S,6'S,E)-1-(2',2',3',6'-tetramethylcyclohexyl)hex-1-en-3-one 
• 153151-38-3 (+)-(1'S,3'S,6'S,E)-1-(2',2',3',6'-tetramethylcyclohexyl)pent-1-en-3-one 
• 140694-26-4 (+)-(1'S,3'S,6'S,E)-4-(2',2',3',6'-tetramethylcyclohexyl)but-3-en-2-one 
• 153061-02-0 (+)-(1R,3S,6S)-2,2,3,6-tetramethylcyclohexane-1-methanol 
• 153061-03-1 (+)-(1S,3S,6S)-2,2,3,6-tetramethylcyclohexane-1-methanol 

Relevant academic research and scientific papers

Preparation of Optically Active Flowery and Woody-Like Odorant Ketones via Corey-Chaykovsky Oxiranylation: Irones and Analogues

α-, β-, and γ-Irones and analogues have been prepared from optically active (+)-1, (+)-6a,b, and (+)-17, via a Corey-Chaykovsky oxiranylation (Me2S, Me2SO4, Me2SO, NaOH) followed by isomerisation (SnCl4 or MgBr2). (+)-Dihydrocyclocitral (19a), obtained from (-)-citronellal, and analogue (+)-19b, were condensed with various ketones to afford (+)-21a-f, and after hydrogenation (+)-22a-f.A mild oxidative degradation of aldehydes (+)-trans- and (-)-cis-8a,b to ketones (-)-16a,b, as well as olfactive evaluations, 13C-NMR assignments, and absolute configurations of the intermediate epoxides, aldehydes, and alcohols are presented.

Tetramethyl-1-oxaspiro[2.5]octane

New 4,4,5,8-tetramethyl-1-oxaspiro[2.5]octane. A process for its preparation starting from 2,2,3,6-tetramethyl-1-cyclohexanone is described. 4,4,5,8-Tetramethyl-1-oxaspiro[2.5]octane is a useful raw material for the preparation of 2,2,3,6-tetramethyl-cyclohexane-carbaldehyde, a key intermediate for the synthetis of valuable fragrance ingredients.