130608-01-4

Upstream product

• 103-26-4 Methyl cinnamate 
• 103-26-4 methyl cinnamate 
• 122743-18-4 methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate 
• 124649-67-8 methyl (2S,3R)-3-phenyl-2,3-dihydroxypropanoate 
• 167357-61-1 (2R,3S)-methyl 2-acetoxy-3-bromo-3-phenylpropanoate 

Downstream Products

• 167275-69-6 methyl (2S)-acetoxy-(3R)-tert-butoxycarbonylamino-3-phenylpropionate 
• 129866-72-4 Methyl (2S,3R)-(-)-2-hydroxy-3-azido-3-phenyl-propionate 

Relevant academic research and scientific papers

Cystobactamids 920-1 and 920-2: Assignment of the Constitution and Relative Configuration by Total Synthesis

Total synthesis of cystobactamid 920-1 and its epimer has allowed an unambiguous assignment of the relative and absolute configuration of the natural product. A careful structural analysis of each isomer using both NMR and computational techniques also pr

CYSTOBACTAMIDES

The present invention provides cystobactamides of formula (I) and the use thereof for the treatment or prophylaxis of bacterial infections:

An efficient synthesis of alterobactin A; a super siderophore of marine origin

Alterobactin A (1), a cyclic depsipeptide and a super siderophore isolated from an open-ocean bacterium, was efficiently synthesized for the first time by a convergent manner with the maximum protection of various functional groups.