13062-91-4Relevant academic research and scientific papers
Biomimetic Phosphate-Catalyzed Pictet-Spengler Reaction for the Synthesis of 1,1′-Disubstituted and Spiro-Tetrahydroisoquinoline Alkaloids
Zhao, Jianxiong,Méndez-Sánchez, Daniel,Ward, John M.,Hailes, Helen C.
, p. 7702 - 7710 (2019)
Tetrahydroisoquinoline (THIQ) alkaloids are an important group of compounds that exhibit a range of bioactivities. Here, a phosphate buffer-catalyzed Pictet-Spengler reaction (PSR) using unreactive ketone substrates is described. A variety of 1,1′-disubst
