130631-95-7Relevant academic research and scientific papers
Aspirin Prodrugs: 2-Methyl-2-aryloxy-4H-1,3-benzodioxin-4-ones Acting as True Aspirin Prodrugs
Hundewadt, Marianne,Senning, Alexander
, p. 746 - 751 (2007/10/02)
This paper is concerned with the synthesis, physical properties and both non-enzymatic and enzymatic in vitro hydrolysis of the title compounds 5.Ten new and two known compounds 5 have been synthesized and characterized.In vitro enzymatic and non-enzymatic hydrolysis of ten compounds 5, including the two known, revealed several of them to behave as true aspirin prodrugs.
