130643-07-1

Basic information

• Product Name: 6-OXA-9-AZASPIRO[4.5]DECANE
• Synonyms: 6-OXA-9-AZASPIRO[4.5]DECANE;OTAVA-BB 1145925;6-oxa-9-azaspiro[4.5]decane(SALTDATA: HCl)
• CAS NO: 130643-07-1
• Molecular Formula: C₈H₁₅NO
• Molecular Weight: 141.21
• Mol File: 130643-07-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 228.1°C at 760 mmHg
• Flash Point: 85°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 0.0746mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: 6-OXA-9-AZASPIRO[4.5]DECANE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-OXA-9-AZASPIRO[4.5]DECANE(130643-07-1)
• EPA Substance Registry System: 6-OXA-9-AZASPIRO[4.5]DECANE(130643-07-1)

Safety Data

• Hazardous Substances Data: 130643-07-1(Hazardous Substances Data)

Usage

Uses

6-?Oxa-?9-?azaspiro[4.5]?decane is used as a reactant in the preparation of spiro-tetracyclic ring compounds as therapeutic secretase modulators.

InChI:InChI=1/C8H15NO/c1-2-4-8(3-1)7-9-5-6-10-8/h9H,1-7H2

Upstream product

• 45511-81-7 1-(aminomethyl)-1-hydroxycyclopentane 
• 5117-85-1 1-hydroxycyclopentanecarbonitrile 
• 120-92-3 cyclopentanone 
• 271245-39-7 1,1-dimethylethyl 6-oxa-9-azaspiro[4.5]decane-9-carboxylate 

Downstream Products

• 1245465-34-2 9-({5-[6-bromo-1-(phenylsulfonyl)-1H-indazol-4-yl]-1,3,4-oxadiazol-2-yl}methyl)-6-oxa-9-azaspiro[4.5]decane 
• 1245465-92-2 C₃₂H₃₀N₆O₄S 
• 1245466-41-4 C₃₁H₃₃N₇O₇S₂ 

Relevant articles and documents

PYRIDOPYRIMIDINE COMPOUNDS ACTING AS MTORC 1/2 DOUBLE-KINASE INHIBITORS

Disclosed are a series of pyridopyrimidine compounds and a use of same in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors, and specifically disclosed is a use of the compounds as shown in formula (IV), tautomers thereof or pharmaceutically acceptable salts thereof in the preparation of drugs associated with mTORC 1/2 dual complex inhibitors.

4-OXADIAZOL-2 -YL- INDAZOLES AS INHIBITORS OF P13 KINASES

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.