1306740-71-5Relevant academic research and scientific papers
Stereoselective synthesis of 2,5-disubstituted pyrrolidines: Via gold-catalysed anti-Markovnikov hydroamination-initiated tandem reactions
Tan, Tong-De,Chen, Yang-Bo,Yang, Ming-Yang,Wang, Jia-Le,Su, Hao-Ze,Hong, Feng-Lin,Zhou, Jin-Mei,Ye, Long-Wu
supporting information, p. 9923 - 9926 (2019/08/22)
A series of gold-catalysed intramolecular anti-Markovnikov hydroamination-initiated azidation, allylation and heteroarylation reactions of chiral homopropargyl sulfonamides have been developed. Various enantioenriched 2,5-disubstituted pyrrolidines are obtained in moderate to excellent yields with excellent enantioselectivities and generally high diastereoselectivities.
Gold-Catalyzed Tandem Cycloisomerization-Halogenation of Chiral Homopropargyl Sulfonamides
Shu, Chao,Li, Long,Shen, Cang-Hai,Ruan, Peng-Peng,Liu, Chao-Yue,Ye, Long-Wu
supporting information, p. 2282 - 2290 (2016/02/12)
Two new gold-catalyzed tandem cycloisomerization-halogenation reactions of chiral homopropargyl sulfonamides have been developed. Various enantioenriched 3,3-diiodopyrrolidin-2-ols and 3-fluoropyrrolidin-2-ols were obtained in moderate-to-good yields with excellent enantio- and diastereoselectivity.
Efficient and practical synthesis of enantioenriched 2,3-dihydropyrroles through gold-catalyzed anti-Markovnikov hydroamination of chiral homopropargyl sulfonamides
Yu, Yong-Fei,Shu, Chao,Zhou, Bo,Li, Jian-Qiao,Zhou, Jin-Mei,Ye, Long-Wu
supporting information, p. 2126 - 2129 (2015/02/05)
A direct gold-catalyzed 5-endo-dig cycloisomerization of chiral homopropargyl sulfonamides has been developed. A range of enantioenriched 2,3-dihydropyrroles are readily accessed by utilizing this approach. Importantly, this gold-catalyzed cycloisomerization reaction proceeds through an anti-Markovnikov addition by using a catalytic base as the additive, which completely suppresses the undesired dimerization. This journal is
Gold-catalyzed intermolecular oxidation of chiral homopropargyl sulfonamides: A reliable access to enantioenriched pyrrolidin-3-ones
Shu, Chao,Li, Long,Yu, Yong-Fei,Jiang, Shuang,Ye, Long-Wu
supporting information, p. 2522 - 2525 (2014/03/21)
A gold-catalyzed intermolecular oxidation of chiral homopropargyl sulfonamides has been developed, which provides a reliable access to synthetically useful chiral pyrrolidin-3-ones with excellent ee, by combining the chiral tert-butylsulfinimine chemistry and gold catalysis. This methodology has also been used in the facile synthesis of natural product (-)-irniine. The use of readily available starting materials, a broad substrate scope, a simple procedure and the mild nature of this reaction render it a viable alternative for the synthesis of enantioenriched pyrrolidin-3-ones.
Gold-catalyzed oxidative cyclization of chiral homopropargyl amides: Synthesis of enantioenriched γ-lactams
Shu, Chao,Liu, Meng-Qi,Wang, Shan-Shan,Li, Long,Ye, Long-Wu
, p. 3292 - 3299 (2013/06/27)
A gold-catalyzed tandem cycloisomerization/oxidation of homopropargyl amides has been developed, which provides ready access to synthetically useful chiral γ-lactams with excellent ee by combining the chiral tert-butylsulfinimine chemistry and gold cataly
