130678-42-1

Basic information

• Product Name: DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE
• Synonyms: (+)-O,O'-BIS(TRIMETHYLSILYL)-L-TARTARIC ACID DIISOPROPYL ESTER;DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL-L-TA RTRATE, FLUKABRAND CHIRASELECT, 99%;(+)-DIISOPROPYL O O'-BIS(TRIMETHYLSILYL&;diisopropyl O,O'-bis(trimethylsilyl) tartrate;(+)-Diisopropyl-O,O`-bis(trMethylsilyl)-L-tartrate;(+)-DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE;DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE
• CAS NO: 130678-42-1
• Molecular Formula: C16H34O6Si2
• Molecular Weight: 378.61
• Mol File: 130678-42-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 105-107 °C1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.972 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.428(lit.)
• Sensitive: Air Sensitive
• CAS DataBase Reference: DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE(130678-42-1)
• EPA Substance Registry System: DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE(130678-42-1)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• F: 3-10-21
• Hazardous Substances Data: 130678-42-1(Hazardous Substances Data)

Usage

General Description

DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE is a chemical compound commonly used as a chiral building block in organic synthesis. It is derived from tartaric acid and contains two trimethylsilyl groups, which can improve the reactivity and selectivity of certain reactions. DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE is used in asymmetric synthesis, particularly in the preparation of chiral ligands and catalysts for asymmetric transformations in organic chemistry. It is also used in the pharmaceutical and agrochemical industries for the production of enantiomerically pure compounds. Overall, DIISOPROPYL O,O'-BIS(TRIMETHYLSILYL)-L-TARTRATE is a valuable and versatile compound with various applications in the field of organic chemistry.

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 2217-15-4 L-(+)-diisopropyl tartrate 

Relevant articles and documents

A New Method for the Stereochemical Analysis of Acyclic Terpenoid Carbonyl Compounds

A new method for the determination of the enantiomeric and diastereoisomeric composition of terpenoid carbonyl compounds is presented.Separation of the diastereomeric (+)-L-diisopropyl-tartrate acetals derived from dihydrocitronellal (6), hexahydropseudoionone (3), hexahydrofarnesal (7), and hexahydrofarnesylacetone (4), the C10, C13, C15, and C18 intermediates in various syntheses of naturally occuring tocopherols and vitamin K1, can be achieved by capillary GC on a cyanopropylsilicon-coated glass column under standardized conditions.This technique, presenting a significant improvment over existing methodologies, is considered to be particularly useful for the analysis of highly enriched samples, typically obtained by present-day asymmetric synthesis.With reproducibilities of +/- 0.3 percent, and therefore, safe for routine analysis, the complete stereochemical characterization of terpenoids with 15 and 18 C-atoms bearing two stereogenic centres is performed in a single operation for the first time.