130697-49-3

Upstream product

• 783-08-4 [4-(benzylideneamino)phenyl]methanol 
• 130632-03-0 1-[(1R,2S,5R)-(-)-(menthyloxycarbonyl)methyl]-2,2,5,5-tetramethyl-2,5-disila-1-azacyclopentane 

Downstream Products

• 1181819-33-9 N-phenyl-N'-[trans-(3S,4S)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-29-3 N-(n-hexyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-34-0 N-(2-chlorophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-38-4 N-(4-trifluoromethylphenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-39-5 N-(4-trifluoromethoxyphenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-43-1 N-(4-cyanophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-36-2 N-(2-fluorophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-32-8 N-phenyl-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-35-1 N-(4-chlorophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-40-8 N-(4-methoxyphenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-37-3 N-(4-fluorophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-41-9 N-(4-azidophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-42-0 N-(4-nitrophenyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 
• 1181819-30-6 N-(cyclohexyl)-N'-[trans-(3R,4R)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-yl]thiourea 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS OF β-LACTAMS BY CHIRAL ESTER ENOLATE-IMINE CONDENSATION

Asymmetric cyclocondensation of N,N-bis(silyl)glycinates bearing chiral ester moieties with aldimines is found to proceed with extremely high enantioselectivity to give the corresponding chiral β-lactams in good to high yields.It is found that the E/Z-geometry of the chiral ester-enolate is responsible for cis/trans stereochemistry of the β-lactam formed.Effects of various chiral auxiliaries in the ester-enolates on the enantioselectivity of the reactions are examined.