130705-32-7

Basic information

• Product Name: N-Formyl-L-leucine (S)-1-<(2S,3S)-2-(Benzyloxy)-3-<(benzyloxy)carbonyl>-3-hexylpropyl>dodecyl Ester
• CAS NO: 130705-32-7
• Molecular Weight: 694.008
• Mol File: 130705-32-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Formyl-L-leucine (S)-1-<(2S,3S)-2-(Benzyloxy)-3-<(benzyloxy)carbonyl>-3-hexylpropyl>dodecyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Formyl-L-leucine (S)-1-<(2S,3S)-2-(Benzyloxy)-3-<(benzyloxy)carbonyl>-3-hexylpropyl>dodecyl Ester(130705-32-7)
• EPA Substance Registry System: N-Formyl-L-leucine (S)-1-<(2S,3S)-2-(Benzyloxy)-3-<(benzyloxy)carbonyl>-3-hexylpropyl>dodecyl Ester(130705-32-7)

Safety Data

• Hazardous Substances Data: 130705-32-7(Hazardous Substances Data)

Upstream product

• 5338-45-4 N-formyl-L-leucine 
• 130793-32-7 benzyl (2S,3S,5R)-3-(benzyloxy)-2-hexyl-5-hydroxyhexadecanoate 

Downstream Products

• 130676-66-3 (2S,3S,5S)-5-<<(S)-2-(Formylamino)-4-methylpentanoyl>oxy>-2-hexyl-3-hydroxyhexadecanoic Acid 
• 130676-65-2 N-Formyl-L-leucine (3S,4S,6S)-3-Hexyl-3,4,5,6-tetrahydro-2-oxo-6-undecyl-2H-pyran-4-yl Ester 

Relevant articles and documents

Tetrahydrolipstatin: Thermal and hydrolytic degradation

The thermal and hydrolytic degradation of tetrahydrolipstatin (THL, 1) was investigated. All main degradation products were isolated, characterized, and synthesized. Labile intermediates unavailable to isolation were detected and identified by GC/MS analysis of their silylated derivatives, and whenever possible, compared with independently prepared reference compounds. The identified degradation products represent at least 97% of the total degradation mixture. Two main reaction pathways are proposed. Pharmacological data are reported for the degradation mixture and the main degradation products.