130708-97-3Relevant academic research and scientific papers
Catalytic Enantioselective Synthesis of N,N-Acetals from α-Dicarbonyl Compounds Using Chiral Imidazoline-Phosphoric Acid Catalysts
Nakamura, Shuichi,Wada, Tatsumi,Takehara, Tsunayoshi,Suzuki, Takeyuki
, p. 5374 - 5379 (2020/10/28)
The enantioselective synthesis of chiral N,N-acetals derived from α-dicarbonyl compounds has been achieved. Good yields and enantioselectivities were observed for the reaction with various α-dicarbonyl compounds with 2-aminobenzamides using chiral bis(imidazoline)-phosphoric acid catalysts. Based on these experimental investigations, a possible transition state is proposed to explain the origin of the asymmetric induction. (Figure presented.).
Cephalosporin compounds
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, (2008/06/13)
Cephalosporin compounds of the formula: wherein R1 is amino or protected amino; R2 is substituted or unsubstituted heterocyclic group having 1 - 3 hetero atoms selected from oxygen and sulphur; R3 is carboxyl or protected carboxyl; R4 is nucleo
