130714-47-5 Usage
Uses
Adenosine receptors are potential therapeutic targets for cerebral and cardiac ischaemic diseases, sleep disorders, immune and inflammatory disorders and cancer. N-Cyclohexyl-2''-O-methyladenosine is an inhibitor of adenosine deaminase-induced lipolysis and a selective adenosine A1-R agonist.
Biological Activity
Potent and selective A 1 adenosine receptor agonist (K i values are 23, > 10000 and 25000 nM for A 1 , A 2A and A 2B receptors respectively). Causes a sustained fall in blood pressure and heart rate in spontaneous hypertensive rats and inhibits adenosine deaminase-stimulated lipolysis in rat adipocytes (K i = 8 nM).
Check Digit Verification of cas no
The CAS Registry Mumber 130714-47-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,7,1 and 4 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 130714-47:
(8*1)+(7*3)+(6*0)+(5*7)+(4*1)+(3*4)+(2*4)+(1*7)=95
95 % 10 = 5
So 130714-47-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H25N5O4/c1-25-14-13(24)11(7-23)26-17(14)22-9-20-12-15(18-8-19-16(12)22)21-10-5-3-2-4-6-10/h8-11,13-14,17,23-24H,2-7H2,1H3,(H,18,19,21)/t11-,13-,14-,17-/m1/s1
