130714-72-6

Basic information

• Product Name: Boc-Leu-DHCGA
• CAS NO: 130714-72-6
• Molecular Weight: 398.456
• Mol File: 130714-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Boc-Leu-DHCGA(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Leu-DHCGA(130714-72-6)
• EPA Substance Registry System: Boc-Leu-DHCGA(130714-72-6)

Safety Data

• Hazardous Substances Data: 130714-72-6(Hazardous Substances Data)

Upstream product

• 3392-09-4 Boc-Leu-ONSu 
• 115730-35-3 (+/-) 1-Amino-2-cyclohexene-1,3-dicarboxylic Acid 
• 130714-74-8 Boc-Leu-DHCGA-dibenzylester 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 37051-56-2 5-Oxo-2-cyclohexenecarboxylic acid 
• 130714-70-4 2,4-Dioxo-1,3-diaza-spiro[4.5]dec-8-ene-7-carboxylic acid 

Downstream Products

• 115730-38-6 (R)-(-)-1-Amino-2-cyclohexene-1,3-dicarboxylic Acid 
• 115730-35-3 (S)-(+)-1-Amino-2-cyclohexene-1,3-dicarboxylic Acid 
• 130714-77-1 (R)-3-((S)-2-Amino-4-methyl-pentanoylamino)-cyclohex-1-ene-1,3-dicarboxylic acid 
• 130714-76-0 (S)-3-((S)-2-Amino-4-methyl-pentanoylamino)-cyclohex-1-ene-1,3-dicarboxylic acid 

Relevant articles and documents

Synthesis and resolution of DHCGA, a new conformationally rigid 3,4-dehydroglutamic acid analogue

(±)-1-amino-2-cyclohexene-1,3-dicarboxylic acid (DHCGA),an unsaturated cyclic analogue of glutamic acid, was prepared from 3-carboxy-4-cyclohexenone by a Bucherer-Bergs reaction. Resolution was performed through coupling with L-leucine and separation of the resulting diastereoisomeric dipeptides. Spectral data, including optical rotation and circular dichroism of both enantiomers of DHCGA are reported.