1307299-76-8

Basic information

• Product Name: (Z)-5-[(E)-3-phenylallylidene]-3-[(7-hydroxy-2-oxo-2H-chromen-4-yl)methyl]thiazolidine-2,4-dione
• Synonyms: (Z)-5-[(E)-3-phenylallylidene]-3-[(7-hydroxy-2-oxo-2H-chromen-4-yl)methyl]thiazolidine-2,4-dione
• CAS NO: 1307299-76-8
• Molecular Weight: 405.431
• Mol File: 1307299-76-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-5-[(E)-3-phenylallylidene]-3-[(7-hydroxy-2-oxo-2H-chromen-4-yl)methyl]thiazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-5-[(E)-3-phenylallylidene]-3-[(7-hydroxy-2-oxo-2H-chromen-4-yl)methyl]thiazolidine-2,4-dione(1307299-76-8)
• EPA Substance Registry System: (Z)-5-[(E)-3-phenylallylidene]-3-[(7-hydroxy-2-oxo-2H-chromen-4-yl)methyl]thiazolidine-2,4-dione(1307299-76-8)

Safety Data

• Hazardous Substances Data: 1307299-76-8(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 1307299-82-6 C₁₃H₉NO₅S 
• 5835-54-1 (5Z)-5-[(E)-3-phenylallylidene]thiazolidine-2,4-dione 
• 161798-25-0 4-(bromomethyl)-7-hydroxy-2H-chromen-2-one 

Relevant articles and documents

Design, synthesis and characterization of some novel 3-coumarinyl- 5-aryliden-1,3-thiazolidine-2,4-diones and their antioxidant activity

In our effort to obtain biologically active compounds, new 3,5-disubstituted 1,3-thiazolidine-2,4- diones (5a - r) were synthesized. A series of 5-arylmethylidene-1,3-thiazolidine-2,4-diones (3a - r) were prepared by Knoevenagel reaction from 1,3-thiazolidine-2,4-dione (2) and appropriate aromatic aldehydes. Condensation of 3a - r with 7-hydroxy-4-bromomethyl-2-oxo- 2H-chromene (1) afforded novel 3-(7-hydroxy-2-oxo-2H-chromen-4-ylmethyl)-5- arylidene-1,3-thiazolidine-2,4-diones 5a - r. Compounds 3a - r and 5a - r were evaluated for their antioxidant activity (DPPH free radical scavenging activity).