130747-38-5Relevant academic research and scientific papers
Reaction of Biguanides and Related Compounds. XVI. Synthesis of s-Triazinones and Fused s-Triazinones by Carbonylation of Biguanides and Related Compounds with Diethyl Azodicarboxylate
Kihara, Yoshito,Kabashima, Shigeru,Yamasaki, Tetsuo,Ohkawara, Tadashi,Furukawa, Mitsuru
, p. 1213 - 1216 (2007/10/02)
Biguanides and the related compounds, in which a moiety of biguanide is involved in the structure as a part of the ring, were allowed to react with diethyl azodicarboxylate to afford triazinones and fused heterocycles including a triazinone ring, respectively.The mechanism of the reaction was elucidated to proceed through the initial formation of the amide intermediate, followed by cyclization to triazinone ring systems with elimination of nitrogen.
