130749-97-2

Upstream product

• 50-00-0 formaldehyd 
• 96-31-1 N,N'-Dimethylurea 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 147806-16-4 (E)-4-<1-(((triisopropylsilyl)oxy)methyl)-1-propenyl>-1-<1-(2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>benzoyl)>cyclopentene 
• 152425-14-4 (4R)-4-<1-((triisopropylsiloxy)methyl)-3-tert-butoxy-1(E)-propenyl>-1-<1-(2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>benzoyl)>cyclopentene 
• 639-43-0 akuammicine 
• 152425-16-6 (1S,3R,5R)-3-<1(E)-(1-((trifluoroacetamido)methyl)-3-tert-butoxypropenyl)>-1-<1-<2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>phenyl>ethenyl>-6-oxabicyclo<3.1.0>hexane 
• 163980-18-5 5-(2-{1-[(1S,5R,7R)-4-[2-tert-Butoxy-eth-(E)-ylidene]-7-hydroxy-2-(2,2,2-trifluoro-acetyl)-2-aza-bicyclo[3.2.1]oct-7-yl]-vinyl}-phenyl)-1,3-dimethyl-[1,3,5]triazinan-2-one 
• 163980-16-3 (1S,3R,5R)-3-<1(E)-(1-((triisopropylsilyl)oxy)methyl-3-tert-butoxypropenyl)>-1-<1-<2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>phenyl>ethenyl>-6-oxabicyclo<3.1.0>hexane 
• 152425-18-8 (1R,7R,8S)-2-((2-tert-butoxy)-1(E)-ethylidene)-7-<2-<5-(1,3-dimethylhexahydro-2-oxa-1,3,5-triazinyl)>phenyl>-4-azatricyclo<5.2.2.0^4,8>undecan-11-one 
• 152425-17-7 (1S,5R,7R)-4-((2-tert-butoxy)-1(E)-ethylidene)-7-hydroxy-7-<1-<2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>phenyl>ethenyl>-2-zabicyclo<3.2.1>octane 
• 152425-15-5 (1S,3R,5R)-3-<1(E)-(1-(hydroxymethyl)-3-tert-butoxypropenyl)>-1-<1-<2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>phenyl>ethenyl>-6-oxabicyclo<3.1.0>hexane 
• 57-24-9 strychnidin-10-one 
• 466-85-3 (17R,19E)-17,18-epoxy-cur-19-en-17-ol 
• 164106-61-0 (1R,3S,5S)-3-<1(E)-(1-<((triisopropylsilyl)oxy)methyl>-3-tert-butoxypropenyl)>-1-<2-<5-(1,3-dimethylhexahydro-2-oxo-1,3,5-triazinyl)>benzoyl>-6-oxabicyclo<3.1.0>hexane 

Relevant academic research and scientific papers

The aza-Cope-Mannich approach to Strychnos alkaloids. Short stereocontrolled total syntheses of (±)-dehydrotubifoline and (±)-akuammicine

A direct approach for the total synthesis of Strychnos alkaloids has been developed. The key strategic element is the aza-Cope-Mannich rearrangement (Scheme II) of formaldiminium ions derived from azabicyclo[3.2.1]octanols 5 (Scheme I). This reorganizatio

Amino protection using triazones

Primary amines protected by incorporation into a "triazone" derivative (3) are stable to various reduction, oxidation, organometallic, and basic hydrolysis conditions, and may be regenerated by treatment with aqueous ammonium chloride at 70°. An application to polyamine synthesis is described.