130756-35-3

Upstream product

• 528-43-8 Magnolol 
• 60594-22-1 caryophyllene oxide 
• 1213270-06-4 C₂₀H₃₀BNO₄ 
• 1213270-10-0 C₂₆H₃₅BrO₃ 
• 1213270-08-6 C₂₁H₂₉BrO₂ 
• 1213270-15-5 C₂₃H₃₁BrO₃ 
• 1213270-09-7 C₂₃H₃₀Br₂O₃ 
• 1213270-14-4 C₁₄H₁₉NO₂ 
• 106-41-2 4-bromo-phenol 
• 501-92-8 4-(prop-2-enyl)phenol 
• 1139-30-6 Caryophyllene oxide 
• 1139-30-6 caryophyllene oxide 
• 87-44-5 β-caryophyllene 
• 126654-54-4 eudesmagnolol 

Downstream Products

• 143051-80-3 Acetic acid (3S,3aS,6R,7R,9aS)-3-(2'-acetoxy-5,5'-diallyl-biphenyl-2-yloxy)-1,1,7-trimethyl-decahydro-3a,7-methano-cyclopentacycloocten-6-yl ester 

Relevant academic research and scientific papers

STRUCTURE OF CLOVANEMAGNOLOL, A NOVEL NEUROTROPHIC SESQUITERPENE-NEOLIGNAN FROM MAGNOLIA OBOVATA

The structure of novel sesquiterpene-neolignan, clovanemagnolol (1), isolated from the bark of Magnolia Obovata has been elucidated on the basis of the extensive 2D-NMR analyses and finally substantiated by one-step biomimetic synthesis from caryphyllene

Neuronal growth promoting sesquiterpene-neolignans; Syntheses and biological studies

The use of small molecules that can promote neuronal growth represents a promising approach to regenerative science. Along these lines we have developed separate short or modular syntheses of the natural products caryolanemagnolol and clovanemagnolol, sma

Hippocampal and cortical neuronal growth mediated by the small molecule natural product clovanemagnolol

The use of small molecule surrogates of growth factors that directly or indirectly promote growth represents an attractive approach to regenerative medicine. With synthetic access to clovanemagnolol, a small molecule initially isolated from the bark of th

Biomimetic syntheses of the neurotrophic natural products caryolanemagnolol and clovanemagnolol

"Chemical Equation Presented" Separate short and modular syntheses of the isomeric natural products caryolanemagnolol and clovanemagnolol have been achieved starting from commercially available (-)-caryophyllene. The postulated biosynthetic pathways guided the syntheses of the neuroregenerative small molecules allowing their assembly In as few as two steps.

NEUROTROPHIC SESQUITERPENE-NEOLIGNANS FROM MAGNOLIA OBOVATA: STRUCTURE AND NEUROTROPHIC ACTIVITY

Novel sesquiterpene-neolignans, eudesobovatols A (1) and B (2), eudesmagnolol (3), eudeshonokiols A (4) and B (5), clovanemagnolol (6), and caryolanemagnolol (7), have been isolated from the bark of Magnolia obovata.Their structures were elucidated to be sesquiterpenes (eudesmol, 4,4,8-trimethyltricyclo2,5>dodecane-1,9-diol, and clovanediol) combined through ether bond with neolignans such as obovatol, honokiol, and magnolol on the basis of spectral data, degradation, and/or synthesis.Compounds 1, 6, and 7 were found to exhibit interesting neurotrophic activity on a neuronal cell culture system derived from fetal rat hemisphere.