130780-50-6

Basic information

• Product Name: 1-(2,4-difluorophenyl)-3,5-dimethylpyrazole
• CAS NO: 130780-50-6
• Molecular Weight: 208.211
• Mol File: 130780-50-6.mol

Chemical Properties

• CAS DataBase Reference: 1-(2,4-difluorophenyl)-3,5-dimethylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-difluorophenyl)-3,5-dimethylpyrazole(130780-50-6)
• EPA Substance Registry System: 1-(2,4-difluorophenyl)-3,5-dimethylpyrazole(130780-50-6)

Safety Data

• Hazardous Substances Data: 130780-50-6(Hazardous Substances Data)

Upstream product

• 40594-30-7 2,4-difluorophenylhydrazine 

Relevant articles and documents

Oxone-DMSO Triggered Methylene Insertion and C(sp2)-C(sp3)-H-C(sp2) Bond Formation to Access Functional Bis-Heterocycles

Metal-free insertion of a methylene group was achieved for the construction of a new C(sp2)-C(sp3)-H-C(sp2) bond in order to prepare novel bis-heterocyclic scaffolds. The complete mechanistic investigations included experimental study and DFT calculations, and various symmetric and unsymmetric bis-pyrazoles as well as other pyrazole-based bis-heterocyclic molecules were prepared in moderate to high yields. Further modification of the bridged methylene group in the unsymmetric pyrazoles generated a chiral center to extend the scope of this method.