1307901-42-3Relevant articles and documents
Zinc-mediated enantioselective addition of terminal 1,3-diynes to N-arylimines of trifluoropyruvates
Zhang, Fa-Guang,Ma, Hai,Zheng, Yan,Ma, Jun-An
, p. 7663 - 7669 (2012)
A facile and effective enantioselective addition of terminal 1,3-diynes to acyclic α-CF3 ketimine esters has been developed by using zinc/Binol complexes. The reaction works well with a variety of aromatic-, aliphatic- and silyl-substituted diynes, providing the desired products in up to 97% yield and 97% enantiomeric excess.