13081-75-9 Usage
General Description
Ethyl 2-Methyl-4-oxo-1,4-dihydropyridine-3-carboxylate is a chemical compound with the molecular formula C10H13NO3. It is a dihydropyridine derivative, which is a class of compounds known for their pharmacological properties, particularly as calcium channel blockers. Ethyl 2-Methyl-4-oxo-1,4-dihydropyridine-3-carboxylate is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It may also have potential applications in the development of new drugs and medical treatments. Overall, this compound plays an important role in medicinal chemistry and biochemical research due to its unique structural and functional properties.
Check Digit Verification of cas no
The CAS Registry Mumber 13081-75-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,8 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 13081-75:
(7*1)+(6*3)+(5*0)+(4*8)+(3*1)+(2*7)+(1*5)=79
79 % 10 = 9
So 13081-75-9 is a valid CAS Registry Number.
13081-75-9Relevant articles and documents
Synthesis of 2,3-disubstituted 4-pyridone from a β-aminocarboxylate derivative and acetoacetate
Sobczak, Adam,Antkowiak, Wieslaw Z.
, p. 2993 - 3001 (2005)
The reaction of diethyl aminomethylenemalonate with ethyl acetoacetate proceeded, when catalyzed by anhydrous hydrogen chloride, toward a respectively substituted α- instead of γ-pyridone derivative formation, contrary to the literature report. Additionally, it was found that the amine used as a starting component in this reaction showed a great tendency to autocondensation under the influence of anhydrous hydrogen chloride to yield 5-ethoxycarbonyl-2- pyridone. The most convenient method to prepare 4-pyridone 2,3-disubstituted derivative appeared to be a three-step synthesis, starting from a chain enamine formation, which was subjected to cyclization, followed by oxidation of the last intermediate. The usefulness of the stepwise synthesis was demonstrated on the 3-ethoxycarbonyl-2-methyl-4-pyridone preparation as an example. Copyright Taylor & Francis, Inc.
