1308286-01-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 170377-13-6 3-((4-chlorophenyl)(hydroxy)methyl)but-3-en-2-one 

Downstream Products

• 1308285-89-3 (S)-4-((R)-1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-4-methyl-2-phenyloxazol-5(4H)-one 
• 1308285-78-0 (S)-4-((R)-1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-4-isopropy-2-phenyloxazol-5(4H)-one 
• 1359183-67-7 (R)-1-(1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-1H-pyrrole-2-carbaldehyde 
• 1359183-06-4 (R)-1-(1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-1H-pyrrole-2-carbonitrile 
• 1359183-08-6 (S)-1-(1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-1H-pyrrole-2-carbonitrile 
• 1359183-47-3 (R)-1-(1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-4-(2-phenylacetyl)-1H-pyrrole-2-carbonitrile 
• 1359183-61-1 (R)-3-((4-chlorophenyl)(3-(2,2,2-trichloroacetyl)-1H-pyrrol-1-yl)methyl)but-3-en-2-one 
• 1359183-63-3 (R)-3-((2-bromo-4-(2,2,2-trichloroacetyl)-1H-pyrrol-1-yl)(4-chlorophenyl)methyl)but-3-en-2-one 
• 1359183-59-7 (R)-4-acetyl-1-(1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-1H-pyrrole-2-carbonitrile 
• 1359183-65-5 (R)-1-(1-(4-chlorophenyl)-2-methylene-3-oxobutyl)-1H-pyrrole-2,4-dicarbonitrile 
• 1370632-69-1 (4S,5R)-dimethyl 3-acetyl-4-(4-chlorophenyl)-5-(trifluoromethyl)cyclopent-2-ene-1,1-dicarboxylate 
• 1394249-98-9 C₂₆H₂₁ClN₂O₃ 
• 1360158-27-5 (S)-3-((4-chlorophenyl)(diphenylphosphoryl)methyl)but-3-en-2-one 
• 1330174-13-4 benzyl 1-(4-chlorophenyl)-2-methylene-3-oxobutyl(tosyl)carbamate 

Relevant academic research and scientific papers

Multifunctional chiral phosphines-catalyzed highly diastereoselective and enantioselective substitution of Morita-Baylis-Hillman adducts with oxazolones

Multifunctional chiral phosphine (phosphine-thiourea type) L2-catalyzed allylic substitutions of MBH adducts 1 with oxazolones 2 produce the corresponding optically active adducts 3 in good to excellent yields and ee's as well as moderate to good de's und

Novel quinidine-derived organocatalysts for the asymmetric substitutions of O-Boc-protected Morita-Baylis-Hillman adducts

A series of novel quinidine-derived organocatalysts was synthesized and utilized for the asymmetric substitution of O-Boc-protected Morita-Baylis- Hillman adducts with various carbamates and tosylcarbamates, affording the corresponding products in good to high yields (up to 91% yield) with moderate to high ee values (up to 96%ee) under mild conditions. A series of novel quinidine-derived organocatalysts was synthesized and utilized for the asymmetric substitution of O-Boc-protected Morita-Baylis-Hillman adducts with various carbamates and tosylcarbamates, affording the corresponding products in good to high yields (up to 91% yield) with moderate to high ee values (up to 96%ee) under mild conditions.