1308299-21-9Relevant articles and documents
The effect of systematic structural modifications on the antibacterial activity of novel oxazolidinones
Pinter, Gabor,Bereczki, Ilona,Roth, Elizabeth,Sipos, Attila,Varghese, Reny,Udo, Edet Ekpenyong,Ostorhazi, Eszter,Rozgonyi, Ferenc,Phillips, Oludotun Adebayo,Herczegh, Pal
, p. 45 - 55 (2012/01/11)
A novel series of tetraethylene glycol (TEG) triazolyl and squaramide containing oxazolidinones were synthesized and tested for their antibacterial activity against a selected panel of Gram-positive and Gram-negative bacteria. The 4-TEG-triazolyl derivatives were prepared by 'click reaction'. The introduction of the TEG and squaramide groups did not favor antibacterial activity. The three nucleoside-containing oxazolidinones were also prepared by 'click' methodology resulted in weak antibacterial activity.