1308311-41-2Relevant academic research and scientific papers
Stereoselective synthesis of cis-2,5-disubstituted pyrrolidines via Wacker-type aerobic oxidative cyclization of alkenes with tert-butanesulfinamide nucleophiles
Redford, Joanne E.,McDonald, Richard I.,Rigsby, Matthew L.,Wiensch, Joshua D.,Stahl, Shannon S.
, p. 1242 - 1245 (2012/05/20)
Palladium(II)-catalyzed aerobic oxidative cyclization of alkenes with tethered tert-butanesulfinamides furnishes enantiopure 2,5-disubstituted pyrrolidines, originating from readily available and easily diversified starting materials. These reactions are the first reported examples of metal-catalyzed addition of sulfinamide nucleophiles to alkenes.
