130854-69-2

Upstream product

• 31060-10-3 (2R,4R,5S)-2-Chloro-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-oxide 
• 321-98-2 (1S,2R)-(+)-ephedrine 
• 130762-54-8 (2S,4R,5S)-3,4-Dimethyl-2-(4-methoxyphenoxy)-5-phenyl-1,3,2-oxazaphospholidine 2-oxide 

Downstream Products

• 130854-70-5 (2R,4R,5R)-2-(2,5-Dimethoxyphenyl)-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 2-oxide 

Relevant academic research and scientific papers

The Stereochemistry of the Aryl Phosphate/Aryl Phosphonate Rearrangement in 1,3,2-Oxazaphospholidine 2-Oxides

On treatment with LDA/THF (aryloxy)phospholidines in the pseudoephedrine/ephedrine series undergo P-O to P-C rearrangement to afford arylphospholidines with retention of configuration at phosphorus.The stereochemistry of each product was assigned by 1H NM