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130855-56-0

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130855-56-0 Usage

General Description

α-Me-Phe(3-F)-OH, also known as alpha-Methyl-phenylalanine(3-Fluoro)-alcohol, is a chemical compound that consists of a phenylalanine derivative with a methyl group at the alpha position and a hydroxyl group at the terminal carbon. The addition of a fluorine atom at the 3-position of the phenyl ring enhances the compound's pharmacological properties and potentially its bioavailability. This chemical is commonly used as a building block in the synthesis of peptide therapeutics and pharmaceuticals due to its ability to modulate biological activity and improve drug-like properties. Moreover, α-Me-Phe(3-F)-OH may also have potential applications in the development of new drugs for various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 130855-56-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,8,5 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 130855-56:
(8*1)+(7*3)+(6*0)+(5*8)+(4*5)+(3*5)+(2*5)+(1*6)=120
120 % 10 = 0
So 130855-56-0 is a valid CAS Registry Number.

130855-56-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-2-amino-2-methyl-3-(3-fluorophenyl)propionic acid

1.2 Other means of identification

Product number -
Other names (S)-α-methyl(3-fluorophenyl)alanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130855-56-0 SDS

130855-56-0Upstream product

130855-56-0Relevant articles and documents

A new approach to the efficient method for the asymmetric synthesis of (S)-O-, M-, P-fluorophenylalanines and their 2-methyl-substituted analogs

Saghiyan, Ashot S.,Petrosyan, Satenik G.,Manasyan, Luiza L.,Dadayan, Slavik A.,Geolchanyan, Arpine V.,Panosyan, Henry A.,Maleev, Victor I.,Khrustalev, Victor N.

scheme or table, p. 493 - 506 (2011/04/16)

The reactions of asymmetric C-alkylation of glycine and alanine in NiII complexes of their Schiff's bases with modified chiral auxiliaries (S)-2-N-[(N0-2-chlorobenzylprolyl)- amino]benzophenone and (S)-2-N-[N′-(3, 4-dimethylbenzylprolyl)amino]benzophenone by fluorine-substituted benzyl halogenides have been studied. As a result, a highly stereoselective and relatively rapid method for the asymmetric synthesis of (S)-o-, m-, p-fluorophenylalanines and their 2-methyl substituted analogs has been developed.

Asymmetric synthesis of organoelement analogues of natural products; Part 12: General method for the asymmetric synthesis of fluorine-containing phenylalanines and α-methyl(phenyl)alanines via alkylation of the chiral nickel(II) Schiff's base complexes of

Kukhar,Belokon,Soloshonok,Svistunova Yu.,Rozhenko,Kuz'mina

, p. 117 - 120 (2007/10/02)

Nickel(II) complexes of Schiff's bases derived from (S)-o-[(N-benzyl]prolyl)amino]benzophenone [N-(2-benzoylphenyl)-1-benzylpyrrolidine-2-carboxamide] (BBP) and glycine or alanine have been used for asymmetric synthesis of fluoro (S)-phenylalanines and (S

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