1308652-76-7Relevant academic research and scientific papers
Synthesis of tetra-ortho-substituted biaryls using aryltriolborates
Li, Gao-Qiang,Yamamoto, Yasunori,Miyaura, Norio
, p. 1769 - 1773 (2011/09/12)
Tetra-ortho-substituted biaryls were synthesized by cross-coupling between 2,6-disubstituted bromoarenes and aryltriolborates possessing substituents at ortho carbon. The use of a copper(I) halide such as CuCl (20 mol%) with a palladium catalyst was found
Highly efficient carbazolyl-derived phosphine ligands: Application to sterically hindered biaryl couplings
Chun To, Sheung,Yee Kwong, Fuk
supporting information; experimental part, p. 5079 - 5081 (2011/06/10)
A new family of phosphine ligands bearing a bulky carbazolyl scaffold is described. With the combination of ligand 2a and Pd(OAc)2, difficult tri-ortho-substituted biaryl couplings are accomplished smoothly. In particular, the catalyst loading as low as 0.02 mol% of Pd for non-activated 2,6-disubstituted aryl chloride coupling can be achieved.
