1308660-44-7Relevant academic research and scientific papers
β-Cyclodextrin mediated MCR in water: Synthesis of dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives under microwave irradiation
Reddy, G. Rajeshwar,Reddy, T. Ram,Chary, R. Gangadhara,Joseph, Suju C.,Mukherjee, Soumita,Pal, Manojit
, p. 6744 - 6746 (2013)
We report a faster and greener approach for the synthesis of dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives of potential pharmacological interest via a β-CD mediated MCR in water under microwave irradiation.
Wang-OSO3H catalyzed green synthesis of bioactive isoindolo[2,1-a]quinazoline-5,11?dione derivatives: An unexpected observation
Dhananjaya,Venkateshwarlu, Rapolu,Dinne, Naresh Kumar Reddy,Kumar, Avula Mahesh,Mekala, Ramamohan,Anna, Venkateswara Rao,Kapavarapu, Ravikumar,Pal, Manojit
, (2021/11/27)
The sulphonic acid-functionalized Wang resin (Wang-OSO3H) was explored as a polymeric and recoverable acidic catalyst for the synthesis of isoindolo[2,1-a]quinazoline-5,11?dione derivatives under green conditions. Thus the Wang-OSO3H
Synthesis of pyrimido[2,1-a]isoindolone and isoindolo[2,1-a]quinazolinoneviaintramolecular aza-Prins type reaction
Biswas, Subhamoy,Porashar, Bikoshita,Arandhara, Pallav Jyoti,Saikia, Anil K.
supporting information, p. 11701 - 11704 (2021/11/12)
A novel aza-Prins type cyclization reaction involvingN-acyliminium ions and amides is reported for the synthesis of tetrahydropyrimido[2,1-a]isoindole-2,6-dione and 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives in excellent yields. The strategy features inexpensive reagents, mild reaction conditions, and metal-free synthesis of N-heterocyclic frameworks. Further, post-synthetic modification results in the unprecedented formation of its triazole, tetracyclic diazacyclopenta[def]phenanthrene-1,4(9a1H)-dione and carbonyl derivatives.
A new three-component reaction: Green synthesis of novel isoindolo[2,1-a]quinazoline derivatives as potent inhibitors of TNF-α
Kumar, K. Siva,Kumar, P. Mahesh,Kumar, K. Anil,Sreenivasulu,Jafar, Ahamed A.,Rambabu,Krishna, G. Rama,Reddy, C. Malla,Kapavarapu, Ravikumar,Shivakumar,Priya, K. Krishna,Parsa, Kishore V. L.,Pal, Manojit
supporting information; experimental part, p. 5010 - 5012 (2011/06/09)
Concurrent construction of five and six membered fused N-heretocyclic ring was achieved via a conceptually new three-component reaction affording 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-diones as novel inhibitors of TNF-α in vitro. This represents one of the few examples of direct TNF-α inhibition by small molecules.
