Cas 1308667-08-4,(1S,2S,3a<sup>(1)</sup>S,12bS)-1-hydroxy-2,3a<sup>(1)</sup>,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diyl bis(2-methylbenzoate)

1308667-08-4

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Product Name: (1S,2S,3a⁽¹⁾S,12bS)-1-hydroxy-2,3a⁽¹⁾,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diyl bis(2-methylbenzoate)
Synonyms:
CAS NO:1308667-08-4
Molecular Formula:
Molecular Weight: 523.585
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (1S,2S,3a⁽¹⁾S,12bS)-1-hydroxy-2,3a⁽¹⁾,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diyl bis(2-methylbenzoate)(CAS DataBase Reference)
NIST Chemistry Reference: (1S,2S,3a⁽¹⁾S,12bS)-1-hydroxy-2,3a⁽¹⁾,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diyl bis(2-methylbenzoate)(1308667-08-4)
EPA Substance Registry System: (1S,2S,3a⁽¹⁾S,12bS)-1-hydroxy-2,3a⁽¹⁾,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diyl bis(2-methylbenzoate)(1308667-08-4)

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Safety Statements: N/A
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RTECS:
HazardClass: N/A
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Hazardous Substances Data: 1308667-08-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1308667-08-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,0,8,6,6 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1308667-08:
(9*1)+(8*3)+(7*0)+(6*8)+(5*6)+(4*6)+(3*7)+(2*0)+(1*8)=164
164 % 10 = 4
So 1308667-08-4 is a valid CAS Registry Number.

1308667-08-4Upstream product

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1308667-08-4Relevant academic research and scientific papers

Lycorine derivatives and application thereof to pesticides

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Paragraph 0016-0018; 0020-0021; 0028, (2017/11/16)

The invention relates to lycorine compounds with structures from (1-1) to (1-20) represented in the description as well as an application of the lycorine compounds to pesticides. When the lycorine compounds are used as novel insecticides and bactericides, part of the compounds have toxic activity on armyworms, mosquito larvae, cotton bollworms and ostrinia nubilalis and have higher inhibition ratio on wheat scab, potato late blight, rape sclerotinia rot and cucumber gray mold than that of a lycorine matrix.

Activity of lycorine analogues against the fish bacterial pathogen Flavobacterium columnare

Tan, Cheng-Xia,Schrader, Kevin K.,Mizuno, Cassia S.,Rimando, Agnes M.

experimental part, p. 5977 - 5985 (2012/01/06)

In a continuing effort to discover natural products and natural product-based compounds for the control of columnaris disease in channel catfish (Ictalurus punctatus), 17 lycorine analogues were synthesized, including new benzoyl analogues 6-16, and evaluated for antibacterial activity against two isolates (ALM-00-173 and BioMed) of Flavobacterium columnare using a rapid bioassay. Two of the lycorine analogues had greater antibacterial activity than 1-O-acetyllycorine, an analogue of lycorine evaluated previously that is highly active against both isolates. Carbamate analogue 18 (1S,2S,3a 1S,12bS)-2,3a1,4,5,7,12b-hexahydro-1H-[1,3]dioxolo[4,5-j] pyrrolo[3,2,1-de]phenanthridin-1,2-diylbis(o-tolylcarbamate) had the strongest antibacterial activity toward both F. columnare isolates ALM-00-173 and BioMed, with 24-h IC50 values of 3.0 ± 1.3 and 3.9 ± 2.2 mg/L, respectively, and a MIC of 5.5 ± 0 mg/L for both isolates. Compound 18 appears to be the most promising lycorine analogue for future efficacy studies to determine its potential for use as an alternative to the currently used compounds to control columnaris disease in channel catfish.

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