1308761-07-0Relevant articles and documents
Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin- 2-yl)-4-(quinolin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors
Jin, Cheng Hua,Krishnaiah, Maddeboina,Sreenu, Domalapally,Rao, Kota Sudhakar,Subrahmanyam, Vura Bala,Park, Chul-Yong,Son, Jee-Yeon,Sheen, Yhun Yhong,Kim, Dae-Kee
, p. 2633 - 2640 (2011/06/11)
A series of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinolin-6-yl) pyrazoles 14a-e, 15a-e, 17a-c, and 18a-d have been synthesized and evaluated for their ALK5 inhibitory activity in an enzyme assay and in a cell-based luciferase reporter assay. The 6