130889-08-6

Upstream product

• 19362-96-0 2-(1-hydroxybenzyl)acrylonitrile 
• 138597-12-3 3-acetoxy-2-methylene-3-phenylpropionitrile 
• 122-52-1 triethyl phosphite 
• 130889-21-3 Phosphorous acid 2-cyano-1-phenyl-allyl ester diethyl ester 

Downstream Products

• 243119-08-6 2-benzylidene-4-methyl-pent-3-enenitrile 
• 643027-04-7 (E)-4-Phenyl-2-[1-phenyl-meth-(Z)-ylidene]-but-3-enenitrile 

Relevant academic research and scientific papers

Nucleophilic addition of triethyl phosphite to acetates of the Baylis-Hillman adducts: Stereoselective synthesis of (E)- and (Z)-allylphosphonates

Nucleophilic addition of triethyl phosphite to 3-acetoxy-2-methylenealkanenitriles and methyl 3-acetoxy-2-methylenealkanoates provides (2E)-2-(diethoxyphosphorylmethyl)alk-2-enenitriles and methyl (2Z)-2-(diethoxyphosphorylmethyl)alk-2-enoates respectively with good stereoselectivity.

A Convenient Method for the Synthesis of Substituted 2-Methoxycarbonyl- and 2-Cyanoallylphosphonates. The Allyl Phosphite - Allylphosphonate Rearrangement

The thermally induced Arbuzov rearrangement of allyl diethyl phosphites gives, under unprecedented mild conditions, a variety of diethyl allylphosphonates with high stereoselectivity and in high yield.