13091-43-5

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINO-3-BROMO-5-METHYLBENZOIC ACID is used as a synthetic building block for the development of new pharmaceuticals. Its unique structure allows for the creation of diverse drug candidates with potential therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 2-AMINO-3-BROMO-5-METHYLBENZOIC ACID is utilized as a key intermediate in the production of various dyes and pigments. Its chemical composition and reactivity enable the synthesis of a wide range of colorants used in different applications, such as textiles, plastics, and printing inks.
Used in Organic Synthesis and Research:
2-AMINO-3-BROMO-5-METHYLBENZOIC ACID is employed as a valuable intermediate in various organic syntheses and research activities. Its unique functional groups and reactivity make it an essential component in the development of novel chemical compounds and the exploration of new reaction pathways.

InChI:InChI=1/C8H8BrNO2/c1-4-2-5(8(11)12)7(10)6(9)3-4/h2-3H,10H2,1H3,(H,11,12)

Upstream product

• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 108938-16-5 7-bromo-5-methyl-2,3-dihydro-1H-indole-2,3-dione 
• 124807-88-1 2-bromo-4-methyl-α-isonitrosoacetanilide 
• 608-05-9 5-methyl-indole-2,3-dione 
• 1132-40-7 2-hydroxyimino-N-p-tolyl-acetamide 
• 106-49-0 p-toluidine 
• 206551-32-8 methyl 2-amino-3-bromo-5-methyl benzoate 

Downstream Products

• 58530-13-5 3-bromo-5-methyl-benzoic acid 
• 177970-27-3 8-bromo-6-methyl-2H-benzo[d][1,3]oxazine-2,4(1H)-dione 
• 124289-21-0 3-bromo-5-methylbenzonitrile 
• 154257-79-1 2,3-dibromo-5-methylbenzoic acid 
• 55414-71-6 (2-amino-3-bromo-5-methylphenyl)methanol 
• 750585-99-0 3-bromo-2-iodo-5-methylbenzoic acid 
• 324528-81-6 2-amino-3-bromo-5-methylbenzamide 
• 215115-09-6 8-bromo-6-methylquinazolin-4(3H)-one 
• 1279724-55-8 C₁₇H₁₇N₅O₂ 
• 885266-83-1 C₁₀H₉BrN₂O 
• 1268520-84-8 C₁₁H₁₁N₃O₂ 
• 151446-28-5 2-amino-3-bromo-5-methylbenzaldehyde 
• 206551-32-8 methyl 2-amino-3-bromo-5-methyl benzoate 

Relevant academic research and scientific papers

Bicyclic heteroaryl compound with PAR4 antagonistic activity and application thereof

The invention discloses a bicyclic heteroaryl compound with PAR4 antagonistic activity and application thereof. The invention provides the bicyclic heteroaryl compound with PAR4 antagonistic activity,and the bicyclic heteroaryl compound has remarkable antagonistic activity on PAR4 in an in-vitro anti-platelet aggregation experiment, so that platelet aggregation is effectively inhibited, and the bicyclic heteroaryl compound can be used for preparing medicines for preventing or treating various thromboembolic diseases.

QUINAZOLINE DERIVATIVES USED TO TREAT HIV

Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and methods of using and making such compounds.

Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors

Intra-molecular hydrogen bonding was introduced to the quinazoline motif to form a pseudo ring (intra-molecular H-bond scaffold, iMHBS) to mimic our previous published core structures, pyrido[2.3-D]pyrimidin-7-one and pteridinone, as PI3K/mTOR dual inhibitors. This design results in potent PI3K/mTOR dual inhibitors and the purposed intra-molecular hydrogen bonding structure is well supported by co-crystal structure in PI3Kγ enzyme. In addition, a novel synthetic route was developed for these analogs.

The synthesis of C2-symmetric and axially chiral compounds for recognition and catalysis

Axially chiral amidines and guanidines, some possessing C2-symmetry, have been targeted as potential chiral catalysts for reactions of α,β-unsaturated carboxylic acids or esters. The key step in each synthesis required the coupling of two sterically demanding aromatic compounds to form atropisomeric biaryl species. (C) 2000 Elsevier Science Ltd.

Synthesis of 3,4-Dihydro-1,4-ethenonaphthalen-2(1H)-ones by Benzyne Cycloadditions.

As part of a project on the photochemistry of 3,4-dihydro-1,4-ethanonaphthalen-2(1H)-ones (benzobicyclooctanones), we were interested in preparing the model 9-ene precursors shown in Scheme 1.On the basis of previous work, it was envisaged that the