1309283-31-5

Basic information

• Product Name: 2-(1-Piperazinyl)pyriMidine
• Synonyms: Buspirone EP Impurity A-d8;2-(1-Piperazinyl)pyrimidine-d8;[2H8]-2- (1-Piperazinyl)pyrimidine
• CAS NO: 1309283-31-5
• Molecular Formula: C8H12N4
• Molecular Weight: 164.20768
• Product Categories: Heterocycles;Isotope Labelled Compounds;Metabolites & Impurities;Mutagenesis Research Chemicals
• Mol File: 1309283-31-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 2-(1-Piperazinyl)pyriMidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-Piperazinyl)pyriMidine(1309283-31-5)
• EPA Substance Registry System: 2-(1-Piperazinyl)pyriMidine(1309283-31-5)

Safety Data

• Hazardous Substances Data: 1309283-31-5(Hazardous Substances Data)

Usage

Description

2-(1-Piperazinyl)pyrimidine is an organic compound that is primarily known as the major metabolite of Tandospirone (T006430), a pharmaceutical drug. It is characterized by its chemical structure, which includes a piperazine group attached to a pyrimidine ring. 2-(1-Piperazinyl)pyriMidine has been found to have various applications in the pharmaceutical and medical fields due to its unique properties.

Uses

Used in Pharmaceutical Applications:
2-(1-Piperazinyl)pyrimidine is used as an active metabolite for the enhancement of Tandospirone's therapeutic effects. As a metabolite of Tandospirone, it plays a crucial role in the drug's overall efficacy and contributes to its pharmacological actions.
Used in Research and Development:
In the field of pharmaceutical research and development, 2-(1-Piperazinyl)pyrimidine serves as a valuable compound for studying the mechanisms of action, pharmacokinetics, and potential applications of Tandospirone and other related drugs. This helps in the development of new drugs with improved efficacy and safety profiles.
Used in Drug Metabolism Studies:
2-(1-Piperazinyl)pyrimidine is used as a reference compound in drug metabolism studies, particularly for understanding the metabolic pathways and enzyme interactions involved in the conversion of Tandospirone to its active metabolite. This information is essential for optimizing drug dosages and minimizing potential side effects.
Used in Quality Control and Standardization:
In the pharmaceutical industry, 2-(1-Piperazinyl)pyrimidine is utilized as a reference standard for quality control and standardization of Tandospirone-containing products. This ensures the consistency, purity, and potency of the drug, which is crucial for maintaining its therapeutic effectiveness and safety.