1309315-11-4

Upstream product

• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 859536-33-7 5-chloro-2-ethanesulfonyl-pyridine 
• 1137917-04-4 (R)-1-(triisopropylsilyloxy)propan-2-yl methanesulfonate 
• 752242-65-2 3-(6-ethanesulfonylpyridin-3-yloxy)-5-hydroxybenzoic acid methyl ester 

Downstream Products

• 1137917-10-2 3-(6-ethanesulfonylpyridin-3-yloxy)-5-((S)-2-hydroxy-1-methylethoxy)benzoic acid 
• 1137917-12-4 bis[3-(6-ethanesulfonylpyridin-3-yloxy)-5-((S)-2-hydroxy-1-methylethoxy)benzoic acid] 1,4-diazabicyclo[2.2.2]octane salt 
• 1137916-97-2 3-(6-ethanesulfonylpyridin-3-yloxy)-5-((S)-2-hydroxy-1-methylethoxy)-N-(1-methyl-1H-pyrazol-3-yl)benzamide methanesulfonic acid salt 

Relevant academic research and scientific papers

A large-scale synthesis of potent glucokinase activator MK-0941 via selective o -arylation and o -alkylation

An efficient, practical preparation of MK-0941, a potent glucokinase activator, is described. Keys to the success of the synthesis are a highly selective mono-O-arylation of methyl 3,5-dihydroxybenzoate with 2-ethanesulfonyl-5-chloropyridine and the choic

METHOD FOR PRODUCING PYRAZOL-3-YL-BENZAMIDE DERIVATIVE

The present invention provides a more efficient industrial method for producing a pyrazol-3-yl-benzamide derivative expressed by a formula useful as medicine: wherein R2, R3 and R4 each independently represent a lower alky