1309358-01-7

Basic information

• Product Name: benzyl (2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-β-D-erythro-pent-4-ulopyranoside
• Synonyms: benzyl (2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-β-D-erythro-pent-4-ulopyranoside
• CAS NO: 1309358-01-7
• Molecular Weight: 352.384
• Mol File: 1309358-01-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-β-D-erythro-pent-4-ulopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-β-D-erythro-pent-4-ulopyranoside(1309358-01-7)
• EPA Substance Registry System: benzyl (2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-β-D-erythro-pent-4-ulopyranoside(1309358-01-7)

Safety Data

• Hazardous Substances Data: 1309358-01-7(Hazardous Substances Data)

Upstream product

• 887370-09-4 benzyl-2,3-O-[(2S,3S)-2,3-dimethoxybutan-2,3-dioxy]-β-D-arabinopyranoside 

Downstream Products

• 1309358-02-8 benzyl (2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-4-C-nitromethyl-α-L-xylopyranoside 
• 1309358-03-9 benzyl(2'S,3'S)-2,3-O-[2',3'-dimethoxybutane-2',3'-diyl]-4-C-nitromethyl-β-D-arabinopyranoside 

Relevant articles and documents

An isofagomine analogue with an amidine at the pseudoanomeric position

(3R,4R,5R)-2-Imino-3,4-dihydroxy-5-hydroxymethylpiperidine hydrocloride or isofagomidine was synthesized from d-arabinose in 12 steps and an overall yield of 9.9%. The synthesis proceeded by introduction of an aminomethyl group in the 4-position of d-arabinose and conversion of C-1 into a nitrile. The key step in the synthesis was a copper-catalyzed cyclization of aminonitrile to amidine. Isofagomidine was a potent α-mannosidase inhibitor (Ki = 0.75 μM).