1309382-41-9Relevant academic research and scientific papers
Regioselective alkylation of carbohydrate derivatives catalyzed by a diarylborinic acid derivative
Chan, Lina,Taylor, Mark S.
, p. 3090 - 3093 (2011)
Regioselective, catalyst-controlled monoalkylations of cis-vicinal diol motifs in carbohydrate derivatives, using a diphenylborinic ester precatalyst, are described. Selective installation of benzyl, naphthylmethyl, 4-bromobenzyl and benzyloxymethyl protective groups at a single secondary hydroxy group of ten representative carbohydrate derivatives illustrates the scope of this method. This new mode of catalytic reactivity represents an operationally simple method to access useful monoalkylated building blocks while avoiding the use of stoichiometric quantities of organotin reagents.
