1309435-50-4Relevant academic research and scientific papers
Iridium-catalyzed anti-diastereo- and enantioselective carbonyl (α-trifluoromethyl)allylation from the alcohol or aldehyde oxidation level
Gao, Xin,Zhang, Yong Jian,Krische, Michael J.
supporting information; experimental part, p. 4173 - 4175 (2011/06/20)
A flourish of fluorine: Exposure of α-trifluoromethyl allyl benzoate to alcohols in the presence of an ortho-cyclometalated iridium catalyst results in the generation of aldehyde-allyliridium intermediates to form enantiomerically enriched products of anti-(α-trifluoromethyl)allylation. An identical set of products is obtained from aldehydes under related transfer hydrogenation conditions employing isopropyl alcohol as terminal reductant. Copyright
