1309462-46-1

Basic information

• Product Name: 5-oxo-N₃-phenyl-6-[(1,7-diphenyl-1,5-dihydro-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)]-1-(4-methylphenyl)-1,5-dihydropyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-3-carboxamide
• CAS NO: 1309462-46-1
• Molecular Weight: 682.701
• Mol File: 1309462-46-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-oxo-N₃-phenyl-6-[(1,7-diphenyl-1,5-dihydro-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)]-1-(4-methylphenyl)-1,5-dihydropyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-oxo-N₃-phenyl-6-[(1,7-diphenyl-1,5-dihydro-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)]-1-(4-methylphenyl)-1,5-dihydropyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-3-carboxamide(1309462-46-1)
• EPA Substance Registry System: 5-oxo-N₃-phenyl-6-[(1,7-diphenyl-1,5-dihydro-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)]-1-(4-methylphenyl)-1,5-dihydropyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidine-3-carboxamide(1309462-46-1)

Safety Data

• Hazardous Substances Data: 1309462-46-1(Hazardous Substances Data)

Upstream product

• 1309462-18-7 5-[(1,7-diphenyl-1,5-dihydro-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)]-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one 
• 33101-95-0 2-anilino-N-(4-methylphenyl)-2-oxoethanehydrazonoyl chloride 
• 1214257-68-7 3-[3-(dimethylamino)-2-propenoyl]-1,7-diphenyl-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidin-5-one 

Relevant articles and documents

A Facile one-pot synthesis and antimicrobial activity of pyrido [2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones

A series of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones (8) has been synthesised via reaction of 5-substituted-2-thioxo-2,3-dihydro-1H-pyrido[2, 3-d]pyrimidin-4-one (3) or its methylthio derivative 4 with hydrazonoyl chlorides 5. Alternative syntheses of products 8 were carried out either by reaction of enaminone 1 with 7-amino-1,3-disubstituted[1,2,4]triazolo[4,3-a] pyrimidin-5-one (10) or via the Japp-Klingemann reaction of compound 13. Both conventional thermal and microwave irradiation techniques were used for synthesis of the target products 8 and a comparative study of these techniques using triethylamine or chitosan, as basic catalysts, was carried out. The mechanisms of the reactions under investigation are discussed. In addition, the antimicrobial activity of the newly synthesized products was evaluated.