1309465-25-5Relevant articles and documents
Stereodivergent direct catalytic asymmetric mannich-type reactions of α-isothiocyanato ester with ketimines
Lu, Gang,Yoshino, Tatsuhiko,Morimoto, Hiroyuki,Matsunaga, Shigeki,Shibasaki, Masakatsu
supporting information; experimental part, p. 4382 - 4385 (2011/06/24)
Now accessible: Sterically hindered vicinal tetrasubstituted carbon stereocenters, which are not accessible by asymmetric hydrogenation, were constructed by a catalytic asymmetric C-C bond formation (see scheme; Dpp=diphenylphosphinoyl). By changing the Group 2 metal center, stereodivergent access to α,β-tetrasubstituted α,β-diamino esters was realized. Copyright