130954-47-1

Basic information

• Product Name: Cyclohexanone, 2-[(4-methylphenyl)methylene]-, (2E)-
• CAS NO: 130954-47-1
• Molecular Formula: C14H16O
• Molecular Weight: 200.28
• Mol File: 130954-47-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-[(4-methylphenyl)methylene]-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-[(4-methylphenyl)methylene]-, (2E)-(130954-47-1)
• EPA Substance Registry System: Cyclohexanone, 2-[(4-methylphenyl)methylene]-, (2E)-(130954-47-1)

Safety Data

• Hazardous Substances Data: 130954-47-1(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 137776-59-1 1-(4-methyl-benzylidene-(seqtrans))-cyclohexanone-⁽²⁾-oxime 
• 42792-79-0 2,6-bis(4-methylbenzylidene)cyclohexanone 
• 62643-75-8 1-(4-methoxy-benzylidene-(seqtrans))-3-(4-methyl-benzylidene-(seqtrans))-cyclohexanone-⁽²⁾ 
• 1043913-51-4 C₂₁H₁₉NO₃ 
• 1266550-43-9 (E)-N-(3-(1-hydroxy-2-(4-methylbenzylidene)cyclohexyl)prop-2-ynyl)-4-methyl-N-(3-methylbut-2-enyl)benzenesulfonamide 
• 130954-56-2 1-Methyl-4-[2-methylene-cyclohex-(E)-ylidenemethyl]-benzene 

Relevant articles and documents

Highly efficient and selective synthesis of (E)-α,β-unsaturated ketones by crossed condensation of ketones and aldehydes catalyzed by an air-stable cationic organobismuth perfluorooctanesulfonate

An air-stable cationic organobismuth perfluorooctanesulfonate possessing both acidic and basic characters was synthesized, and showed high catalytic activity, diastereoselectivity, stability, and reusability in the one-pot synthesis of (E)-α,β-unsaturated ketones through highly selective crossed condensation of ketones and aldehydes in water.

Ruthenium-catalysed synthesis of chiral exocyclic allylic alcoholsviachemoselective transfer hydrogenation of 2-arylidene cycloalkanones

An exclusive asymmetric reduction of C=O bonds of 2-arylidene four-, five-, six-, and seven-membered cycloalkanones has been studied systematically. The asymmetric transfer hydrogenation was performed using a robust and commercially available chiral diamine-derived ruthenium complex as a catalyst and HCOOH/Et3N as a hydrogen source under mild conditions, giving 51 examples of chiral exocyclic allylic alcohols in up to 96% yield and 99% ee. This method was also applicable to the gram-scale synthesis of the active intermediates of the anti-inflammatory loxoprofen and natural product (?)-goniomitine.

Establishing the correlation between catalytic performance and N→Sb donor-acceptor interaction: Systematic assessment of azastibocine halide derivatives as water tolerant Lewis acids

A series of organoantimony(iii) halide complexes with a tetrahydrodibenzo[c,f][1,5]azastibocine framework were synthesized and employed as water tolerant Lewis acid catalysts. The results of a systematic structure-activity relationship study demonstrated that the strength of N→Sb donor-acceptor interaction could be synergistically modulated by tuning the properties of the nitrogen substituents and halogen atoms adjacent to the central antimony atom, and consequently resulted in distinct catalytic performances towards organic reactions such as Mannich, cross-condensation, cyclization-aromatization and epoxide aminolysis reaction. The fluorinated organoantimony(iii) derivatives were found to be more active than those of the chlorinated, brominated and iodinated analogues, owing to the use of an Sb-F moiety as a hydrogen bond acceptor. By comparison, the compound 6-cyclohexyl-12-fluoro-5,6,7,12-tetrahydrodibenzo[c,f][1,5] azastibocine (1d) is found to exhibit the highest catalytic activity, together with facile reusability in scale enlarged synthesis.