1309573-60-1

Basic information

• Product Name: DL-alpha-Tocopherol Methoxypolyethylene glycol succinate solution 2 wt. % in H2O
• Synonyms: DL-alpha-Tocopherol Methoxypolyethylene glycol succinate solution 2 wt. % in H2O;DL-α-Tocopherol methoxypolyethylene glycol succinate solution;TPGS-750-M;DL-α-Tocopherol methoxypolyethylene glycol succinate;DL-alpha-Tocopherol methoxypolyethylene glycol succinate
• CAS NO: 1309573-60-1
• Molecular Formula: C6H5F3N2
• Molecular Weight: 162.1125096
• Mol File: 1309573-60-1.mol
• Article Data: 0

Chemical Properties

• Flash Point: >110℃
• Appearance: /
• Density: 0.981 g/mL at 25 °C
• Refractive Index: n20/D1.340
• CAS DataBase Reference: DL-alpha-Tocopherol Methoxypolyethylene glycol succinate solution 2 wt. % in H2O(CAS DataBase Reference)
• NIST Chemistry Reference: DL-alpha-Tocopherol Methoxypolyethylene glycol succinate solution 2 wt. % in H2O(1309573-60-1)
• EPA Substance Registry System: DL-alpha-Tocopherol Methoxypolyethylene glycol succinate solution 2 wt. % in H2O(1309573-60-1)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 1309573-60-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1309573-60-1 differently. You can refer to the following data:
1. Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.Included among the possible reactions are:Olefin metathesisPd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactionsC-H activation reactionsSecond generation amphiphile for cross-coupling reactions in water
2. DL-α-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M), a biodegradable and water-soluble derivative of natural vitamin E, is used as an environmentally benign nonionic surfactant in metal-catalyzed cross-coupling reactions in water. It is used in Heck, Suzuki-Miyaura, Sonogashira, and Negishi like couplings reactions. It can also be utilized in aminations, C-H activations, and olefin metathesis reactions. TPGS-750-M can also be employed in: The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions. The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp2)-H hydroxylation reaction. The intramolecular N-arylation of amines using a copper catalyst.

General Description

This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency.