1309583-99-0Relevant academic research and scientific papers
Iron-catalyzed asymmetric epoxidation of β,β-disubstituted enones
Nishikawa, Yasuhiro,Yamamoto, Hisashi
supporting information; experimental part, p. 8432 - 8435 (2011/07/29)
The combination of Fe(OTf)2 and novel phenanthroline ligands enables the catalytic asymmetric epoxidation of acyclic β,β- disubstituted enones, which have been a heretofore inaccessible substrate class. The reaction provides highly enantioenriched α,β-epoxyketones (up to 92% ee) that can be further converted to functionalized β-ketoaldehydes with an all-carbon quaternary center.
