1309595-75-2

Upstream product

• 1309595-74-1 (3R,4S,6R)-9-(benzyloxy)-6-(4-(methoxybenzyl)oxy)-3-methylnon-1-en-4-ol 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 1309595-73-0 (R)-7-(benzyloxy)-4-((4-methoxybenzyl)oxy)hept-1-ene 
• 127793-67-3 (R)‐7‐(benzyloxy)hept‐1‐en‐4‐ol 
• 112482-35-6 1-(benzyloxy)-4,5-epoxypentane 
• 1026455-24-2 (R)-6-(benzyloxy)-3-(4-(methoxybenzyl)oxy)hexanal 

Downstream Products

• 1309595-76-3 (2R,3S,5R)-8-(benzyloxy)-3,5-bis((4-methoxybenzyl)oxy)-2-methyloctanal 
• 1332361-68-8 C₃₅H₄₆O₆ 

Relevant academic research and scientific papers

Highly demanding cross-metathesis in the synthesis of the C16-C30 fragment of dolabelide C

A highly demanding cross-metathesis (CM) reaction for the formation of the C24-C25 trisubstituted olefin of dolabelide C has been optimized. A difference in reactivity between the E and Z enone isomers in this reaction was uncovered, and the selection of the Z isomer of the starting enone was critical for the success of the cross-metathesis. Application to the synthesis of the C16-C30 fragment of dolabelide C is reported.