130964-40-8

Basic information

• Product Name: N-[2-(P-CINNAMYLAMINO)ETHYL]-5-ISOQUINOLONE SULFONAMIDE
• Synonyms: H-88;N-[2-(P-CINNAMYLAMINO)ETHYL]-5-ISOQUINOLONE SULFONAMIDE
• CAS NO: 130964-40-8
• Molecular Formula: C20H21N3O2S
• Molecular Weight: 367.46464
• Product Categories: Protein Kinase Inhibitors and Activators
• Mol File: 130964-40-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 84-86°C
• Boiling Point: 602.4°C at 760 mmHg
• Flash Point: 318.1°C
• Appearance: /
• Density: 1.247g/cm³
• Vapor Pressure: 1.82E-14mmHg at 25°C
• Refractive Index: 1.639
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 10.44±0.50(Predicted)
• CAS DataBase Reference: N-[2-(P-CINNAMYLAMINO)ETHYL]-5-ISOQUINOLONE SULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(P-CINNAMYLAMINO)ETHYL]-5-ISOQUINOLONE SULFONAMIDE(130964-40-8)
• EPA Substance Registry System: N-[2-(P-CINNAMYLAMINO)ETHYL]-5-ISOQUINOLONE SULFONAMIDE(130964-40-8)

Safety Data

• Hazardous Substances Data: 130964-40-8(Hazardous Substances Data)

Usage

Chemical Properties

Off White Solid

Uses

Different sources of media describe the Uses of 130964-40-8 differently. You can refer to the following data:
1. Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase).
2. Selective inhibitor of Protein Kinase A (cyclic AMP-dependeant Protein Kinase)

InChI:InChI=1/C20H21N3O2S/c24-26(25,20-10-4-9-18-16-22-13-11-19(18)20)23-15-14-21-12-5-8-17-6-2-1-3-7-17/h1-11,13,16,21,23H,12,14-15H2/b8-5+

Relevant articles and documents

Protein kinase inhibitors

Novel isoquinoline derivatives which are useful as inhibitors of protein kinases for experimental, medical, and drug design purposes are disclosed. Preferred compounds which are specific inhibitors of protein kinase B are also disclosed. Furthermore, phar