1309666-81-6Relevant academic research and scientific papers
GPCR ligand dendrimer (GLiDe) conjugates: Adenosine receptor interactions of a series of multivalent xanthine antagonists
Kecskés, Angela,Tosh, Dilip K.,Wei, Qiang,Gao, Zhan-Guo,Jacobson, Kenneth A.
experimental part, p. 1115 - 1127 (2012/04/23)
Previously, G protein-coupled receptor (GPCR) agonists were tethered from polyamidoamine (PAMAM) dendrimers to provide high receptor affinity and selectivity. Here, we prepared GPCR ligand-dendrimer (GLiDe) conjugates from a potent adenosine receptor (AR)
METHANOCARBA ADENOSINE DERIVATIVES AND DENDRIMER CONJUGATES THEREOF
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Page/Page column 8, (2011/06/25)
Disclosed are (N)-methanocarba adenine nucleosides, e.g., of the formula (I): as A3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein A, a, R2, and
