130974-17-3Relevant academic research and scientific papers
138. Electrophilic Substitution Reactions of 1,1-Difluoro-1H-cyclopropabenzene
Neidlein, Richard,Kohl, Matthias
, p. 1497 - 1503 (2007/10/02)
1,1-Difluoro-1H-cyclopropabenzene (1) can be deprotonated with strong bases at C(2).The resulting 1,1-difluoro-2-lithio-1H-cyclopropabenzene (2) reacts with electrophiles to form C(2)-substituted derivatives of 1.The Diels-Alder reactions with electron-poor dienes, characteristic for 1H-cyclopropabenzene, do not occur with the 1,1-difluoro analogue of 1.
