1309767-71-2Relevant academic research and scientific papers
Exploring the reactivity of 1,5-disubstituted sulfonyl-triazoles: Thermolysis and Rh(II)-catalyzed synthesis of α-sulfonyl nitriles This article is dedicated to Professor Paul Wender for both his creative contributions to synthetic organic chemistry and u
Meza-Avi?a, Maria Elena,Patel, Mudita Kishor,Croatt, Mitchell P.
, p. 7840 - 7846 (2013/08/23)
The reactivity of a series of 1,5-disubstituted sulfonyl-triazoles was explored using either thermolytic or metal-catalyzed conditions. Both the thermolysis and the Rh(II)-catalyzed reactions led to the synthesis of α-sulfonyl-nitriles, which presumably o
Selective formation of 1,5-substituted sulfonyl triazoles using acetylides and sulfonyl azides
Meza-Avina, Maria Elena,Patel, Mudita Kishor,Lee, Cylivia B.,Dietz, Thomas J.,Croatt, Mitchell P.
supporting information; experimental part, p. 2984 - 2987 (2011/08/06)
The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide-alkyne cycloaddition. The reaction is efficient and selective with a variety of alkyne sources and sulfonyl azides and can incorporate an additional electrophile to yield 1,4,5-trisubstituted sulfonyl triazoles.
