1309774-10-4

Basic information

• Product Name: 1-(7-bromo-1,5-naphthyridin-2-yl)-3-(2-phenylethyl)urea
• Synonyms: 1-(7-bromo-1,5-naphthyridin-2-yl)-3-(2-phenylethyl)urea
• CAS NO: 1309774-10-4
• Molecular Weight: 371.236
• Mol File: 1309774-10-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(7-bromo-1,5-naphthyridin-2-yl)-3-(2-phenylethyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(7-bromo-1,5-naphthyridin-2-yl)-3-(2-phenylethyl)urea(1309774-10-4)
• EPA Substance Registry System: 1-(7-bromo-1,5-naphthyridin-2-yl)-3-(2-phenylethyl)urea(1309774-10-4)

Safety Data

• Hazardous Substances Data: 1309774-10-4(Hazardous Substances Data)

Upstream product

• 1309774-04-6 7-bromo-1,5-naphthyridine-2-amine 
• 13535-01-8 3-amino-5-bromopyridine 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 64-04-0 phenethylamine 

Relevant articles and documents

Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells

A novel series of (7-aryl-1,5-naphthyridin-2-yl)ureas was discovered as dual ERK2 and Aurora B kinases inhibitors. Several analogues were active at micromolar and submicromolar range against ERK2 and Aurora B, associated with very promising antiproliferat

Novel Naphthyridine derivatives and the use thereof as kinase inhibitors

The present invention relates to kinase modulators of the naphthyridine type and to the preparation and use thereof as medicaments for the modulation of misdirected cellular signal transduction processes, in particular for influencing the function of tyro