1309830-63-4Relevant academic research and scientific papers
Asymmetric aza-Henry reaction of chiral fluoroalkyl α,β- unsaturated N-tert-butanesulfinyl ketoimines: An efficient approach to enantiopure fluoroalkylated α,β-diamines and α,β-diamino acids
Zhang, Fan,Liu, Zhen-Jiang,Liu, Jin-Tao
, p. 3625 - 3628 (2011)
The aza-Henry reaction of chiral fluoroalkyl α,β-unsaturated N-tert-butanesulfinyl ketoimines and nitromethane was achieved in the presence of 0.2 equivalent of anhydrous potassium carbonate to give the corresponding adducts diastereoselectively in high yields. Transformations which highlighted the synthetic potential of these aza-Henry adducts were also performed.
