13099-77-9Relevant academic research and scientific papers
First and second generation of trifluoromethanesulfenamide reagent: A trifluoromethylthiolating comparison
Glenadel, Quentin,Alazet, Sébastien,Billard, Thierry
, p. 89 - 95 (2015/11/09)
Trifluoromethylthiolation of molecules is a more and more studied reaction. In particular, the direct electrophilic trifluoromethylthiolation plays an important role in this chemistry. Among the various developed reagents, trifluoromethanesulfenamides constitute an efficient family of reagents. However, no systematic comparison of these two generations has been realized. In this paper, the difference of reactivity of these reagents is studied towards various nucleophiles.
Synthesis of trifluoromethanesulfinamidines and -sulfanylamides
Ferry, Aurelien,Billard, Thierry,Langlois, Bernard R.,Bacque, Eric
scheme or table, p. 9362 - 9365 (2009/04/11)
(Chemical Equation Presented) Fluorinated moieties constitute important substituents used in many applications to modify the properties of molecules. The action of DAST onto Ruppert's reagent yields to a not isolable intermediate that can then react with various primary amines to give trifluoromethanesulfinamidines and trifluoromethane-sulfanylamides. Such compounds were unknown until now and constitute interesting new families of fluorinated molecules.
