1309952-39-3Relevant academic research and scientific papers
Modular access to N-substituted cis-3,5-diaminopiperidines
Blond, Aurelie,Dockerty, Paul,Alvarez, Raquel,Turcaud, Serge,Lecourt, Thomas,Micouin, Laurent
, p. 12236 - 12242 (2014/01/06)
A sequence of oxidative cleavage/reductive amination/hydrogenolysis enables the preparation of N-substituted cis-3,5-diaminopiperidines from a readily available bicyclic hydrazine. This new synthetic route provides a simple and general access to RNA-friendly fragments with a good chemical diversity.
Stereoselective synthesis of fluorinated 1,3- cis -diaminocyclopentanes
Pasco, Morgane,Moumne, Roba,Lecourt, Thomas,Micouin, Laurent
experimental part, p. 5137 - 5142 (2011/08/06)
Several fluorinated 1,3-diaminocyclopentanes, previously reported to be useful RNA structural probes, can be prepared in a diastereoselective manner from a single bicyclic hydrazine precursor, in 3 to 9 steps.
