1309953-90-9Relevant academic research and scientific papers
A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleic acids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm
Liu, Xin,Sun, Yuming,Zhang, Yuanhong,Miao, Fang,Wang, Guancong,Zhao, Hongshi,Yu, Xiaoqiang,Liu, Hong,Wong, Wai-Yeung
, p. 3615 - 3618 (2011)
A new carbazole-derived dicationic compound, namely 2,7-bis(1-hydroxyethyl- 4-vinylpyridinium iodine)-N-ethylcarbazole (2,7-9E-BHVC), with a large two-photon action absorption cross section in nucleic acids has been obtained. Moreover, it possesses the potential of imaging RNA in nucleoli and cytoplasm in two-photon fluorescence microscopy and exhibits good counterstain compatibility with the commercial fluorescent nucleic dye DAPI.
KIT FOR DETECTING ctDNA AND EXPRESSION OF DRUG-RESISTANT GENES RELATED TO APPLICABILITY OF TUMOR CHEMOTHERAPEUTIC DRUGS
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Paragraph 0028; 0029, (2019/10/23)
A kit for determining ctDNA concentration and a method for determining ctDNA concentration is disclosed, wherein the method comprising dissolving extracted ctDNA in Tris-HCl buffer with pH>7.0 and adding into the buffer 2,7-bis(1-methyl-4-vinylpyridine)-9-ethylcarbazole iodised salt as a molecular probe, calculating the concentration of ctDNA in the solution by measuring the Fluorescence intensity of the solution. It has extremely high sensitivity in the determination of 0 μg/ml?50 μg/ml ctDNA solution.
